Free. No course required.

Dosi University

180+ compounds. What the internet claims vs. what the research actually says. We cut through the influencer noise and break it all down in plain English — for every compound we track. Always free.

180+

Compounds covered

Cost. Always free.

Paid courses needed

100%

Research-backed

Claims vs Reality

For each compound, we list what influencers and paid courses tell you — then what the published research actually supports. No spin. Just science.

What the internet says

x"Wolverine healing factor" — heals literally everything

xFix torn tendons, gut issues, and brain injuries in days

xZero side effects, completely safe for everyone

What the research says

✓Strong animal data for tendon, ligament, and gut mucosal healing — but almost no human clinical trials exist yet

✓Mechanism is real: promotes angiogenesis (new blood vessel growth) and upregulates growth factor receptors

✓Most studies use rats with surgically-induced injuries — dosing, timing, and outcomes don't translate 1:1 to humans

✓Side effect profile is genuinely mild in reported use, but "no side effects" is an overstatement without long-term human data

The Bottom Line

Promising compound with real biological mechanisms. The animal research is compelling, but anyone claiming guaranteed results in humans is ahead of the science. Worth tracking carefully if you use it — which is exactly what Dosi does.

Key study: Sikiric et al., 2018 — Journal of Physiology Paris (comprehensive review of 100+ BPC-157 animal studies)Full BPC-157 deep dive →

What the internet says

x"Magic weight loss drug" — lose 50 lbs without trying

xNo need to change diet or exercise, the drug does everything

xEveryone should be on it, it's basically a miracle

What the research says

✓FDA-approved with robust clinical data: STEP trials showed ~15% body weight reduction over 68 weeks — real, but not magic

✓Works by mimicking GLP-1 hormone: slows gastric emptying, reduces appetite, improves insulin sensitivity

✓Diet and exercise still matter — participants who combined lifestyle changes saw the best results

✓GI side effects (nausea, vomiting, diarrhea) affect 40-50% of users, especially during dose titration

✓Muscle mass loss is a real concern: ~40% of weight lost can be lean mass without resistance training

The Bottom Line

One of the most effective weight loss medications ever developed — with real clinical evidence behind it. But it's not a free pass. Nausea is common, muscle loss is real, and weight often returns if you stop. Track your doses, side effects, and body composition carefully.

Key study: Wilding et al., 2021 — NEJM (STEP 1 trial: semaglutide 2.4mg vs placebo, n=1,961)Full Semaglutide deep dive →

What the internet says

x"Ozempic killer" — twice as effective, fewer side effects

xLose 25%+ of body weight guaranteed

xMakes semaglutide obsolete

What the research says

✓Dual GIP/GLP-1 agonist — genuinely different mechanism than semaglutide (targets two hormones, not one)

✓SURMOUNT-1 trial: 22.5% weight loss at highest dose over 72 weeks — the most in any obesity drug trial to date

✓GI side effects are similar to semaglutide, not dramatically better: nausea (24-33%), diarrhea (17-23%)

✓Head-to-head data vs semaglutide is limited — the "twice as effective" claim comes from cross-trial comparison, which is unreliable

✓Long-term cardiovascular outcomes data (SELECT-equivalent) is still being collected

The Bottom Line

The weight loss numbers are real and impressive. But "Ozempic killer" is marketing, not science — different drugs work differently for different people. The dual mechanism is genuinely novel. Track your response and let your data tell you what works for YOUR body.

Key study: Jastreboff et al., 2022 — NEJM (SURMOUNT-1: tirzepatide vs placebo, n=2,539)Full Tirzepatide deep dive →

What the internet says

xUltimate recovery peptide — heals anything BPC-157 can't

xUsed by pro athletes and racehorses for instant recovery

xStack with BPC-157 for the "Wolverine Stack" — guaranteed healing

What the research says

✓TB-500 is a synthetic fragment of Thymosin Beta-4, which IS involved in cell migration, wound healing, and inflammation regulation

✓Most research is in cardiac tissue repair (mouse models of heart attack) — not sports injuries

✓The horse racing connection is real but misleading: it was banned not because it worked miraculously, but because it was undetectable and widespread

✓Human clinical trial data is extremely limited — far less than even BPC-157

✓"Wolverine Stack" is a community invention, not a studied protocol — no controlled trials on the combination

The Bottom Line

Real biological activity, extremely limited human evidence. The community enthusiasm is way ahead of the science. If you're using it, you're essentially self-experimenting — log everything.

Key study: Sosne et al., 2015 — Expert Opinion on Biological Therapy (Thymosin Beta-4 review)Full TB-500 deep dive →

What the internet says

xInstant energy, muscle, and libido boost within days

x200mg/week is the standard dose for everyone

xNo real risks if you stay in the "normal" range

What the research says

✓Testosterone replacement in clinically hypogonadal men does improve energy, libido, muscle mass, and mood — well-established in multiple RCTs

✓Peak effects take 3-6 months, not days. Libido may improve in weeks; body composition changes take months

✓Dosing is highly individual — 100-200mg/week is typical but optimal dosing depends on SHBG, metabolism, and target levels. Cookie-cutter protocols fail many patients

✓Real risks exist: erythrocytosis (thick blood), fertility suppression (HCG may be needed), potential cardiovascular concerns in older men, and acne/hair loss in genetically prone individuals

✓Frequent injection schedules (2x/week or more) reduce peak/trough swings and often reduce side effects

The Bottom Line

TRT is legitimate medicine for men with diagnosed low testosterone. But the bro-science "one size fits all" protocol ignores real individual variation. Get bloodwork, dial in YOUR dose, and track your markers — not someone else's protocol.

Key study: Bhasin et al., 2018 — Journal of Clinical Endocrinology & Metabolism (Endocrine Society TRT Guidelines)Full Testosterone Cypionate deep dive →

What the internet says

xReverses aging at the cellular level

xIV NAD+ infusions will make you feel 20 years younger

xEvery longevity expert takes it — it's the #1 anti-aging compound

What the research says

✓NAD+ levels DO decline with age — this is well-documented. The question is whether supplementing it actually reverses aging outcomes

✓Animal data is promising: NMN/NR (NAD+ precursors) improved metabolic markers in aged mice. But mice are not humans

✓Human trials on NR/NMN show NAD+ levels increase in blood — but downstream anti-aging effects (lifespan extension, disease prevention) are NOT yet proven in humans

✓IV NAD+ infusions are expensive ($500-1500/session) and the bioavailability advantage over oral NMN/NR is debated

✓David Sinclair's enthusiasm popularized NAD+ but drew criticism from peers for overstating conclusions

The Bottom Line

The biology is real — NAD+ matters for cellular energy and repair. But "reverses aging" is a leap the human data doesn't support yet. If you're supplementing, track your biomarkers over time rather than trusting how you "feel" on day one.

Key study: Yoshino et al., 2021 — Science (NMN improves muscle insulin sensitivity in prediabetic women, n=25)Full NAD+ deep dive →

What the internet says

xNatural GH boost without the cost of real HGH

xBetter sleep, fat loss, muscle gain — all from one peptide stack

xCompletely safe because it's "natural" growth hormone release

What the research says

✓Both compounds do stimulate GH release through different mechanisms: CJC-1295 extends GHRH signaling, Ipamorelin mimics ghrelin at the GH secretagogue receptor

✓GH pulses increase — but the magnitude is much less than exogenous HGH injection. You're boosting your own production, not replacing it

✓Sleep improvement is commonly reported and plausible — GH release is naturally pulsatile and tied to deep sleep cycles

✓Fat loss and muscle gain effects are modest and take months — nothing like what exogenous HGH delivers

✓"Natural" doesn't mean risk-free: potential for increased cortisol, water retention, and carpal tunnel-like symptoms. Long-term safety data is absent

The Bottom Line

A reasonable approach to mildly boosting GH output. But anyone expecting HGH-level results from secretagogues is going to be disappointed. Set realistic expectations and track your sleep, body composition, and IGF-1 levels over months, not weeks.

Key study: Teichman et al., 2006 — JCEM (CJC-1295 increases GH and IGF-1 in healthy adults, n=33)Full CJC-1295 + Ipamorelin deep dive →

What the internet says

xFountain of youth for skin — erases wrinkles, reverses aging

xRegrows hair better than minoxidil

xHeals wounds overnight when injected

What the research says

✓GHK-Cu (copper peptide) has legitimate wound-healing research — it promotes collagen synthesis, attracts immune cells, and has anti-inflammatory properties

✓Topical GHK-Cu has shown measurable skin improvement in small studies: increased collagen density and reduced fine lines over 12 weeks

✓Hair growth claims come from a single in-vitro study showing follicle enlargement — no controlled human hair loss trials

✓Injectable GHK-Cu is popular in biohacking but has almost no published human safety or efficacy data for systemic use

✓Copper overload is a theoretical risk with aggressive systemic dosing, especially in people with Wilson's disease or impaired copper metabolism

The Bottom Line

Solid topical peptide with real skin benefits at modest expectations. Injectable use for systemic effects is speculative. The "fountain of youth" framing is classic peptide bro overselling of limited data.

Key study: Pickart et al., 2015 — BioMed Research International (GHK-Cu wound healing and tissue remodeling review)Full GHK-Cu deep dive →